Foods with Phytochemicals – Potential Benefits of Ursolic Acid
Ursolic acid is a phytochemical belonging to the sub class of triterpenoid. This belongs to the Terpenes group which is usually found in apples, basil, lavender, peppermint, oregano, hawthorn, prunes, bilberries, and others. This substance has lot of benefits related to health. They act as multi-drug resistance for cancers. They help in regulating the expressions of apoptosis antagonistic proteins. Ursolic acid is used as supplementary factor for dermal preparations. This is because they are non-toxic in nature and higher amount of cytotoxic activity as against HSF cells. Hence, Ursolic acid is used for qualitative purpose and to control natural products that is used in dermatocosmetalogy. Ursolic acid is used as an antibiotic resistance. It helps in cytotoxic activities as it has anti-proliferative capability of derivatives. Ursolic acid helps in the prevention of hepatocellular carcinoma as it induces human hepatoma cell line and apoptosis. Ursolic acid helps in the treatment of bladder cancers in human as it contains anti-tumor properties that help in increment of the ceramide levels. The analogs of Ursolic acid helps in identifying the active cancer cell lines with the help of QSAR models. Thus it helps in the evaluation of anticancer activity.
Ursolic acid helps in the prevention and treatment of chronic diseases and cancer. It also helps in the evaluation of photo protective effects against UVAR of triterpenoid. Ursolic acid also provides conventional treatment of hypertension jointly with heart failure. The other benefits of Ursolic acid are it reduces the storage of fat and increases burning of fat. This process is effective through the inhabitation in fat cells by improving lipolysis and usage of pancreatic lipase. With the inhibition of fatty acid synthase it helps in reducing the transfer of sugar in blood to fat. It enhances the glycogen storage and helps in increasing the energy levels in the muscles. It helps in the reduction of abdominal fat. It acts as anti-carcinogenic that is induced by inhibiting the activation pathway of STAT3. The cholesterol levels are lowered with the activation of receptors known as peroxisome proliferator. With the aromatose inhibition it increases the estrogen levels. It helps in the strengthening of bones. It helps in differentiation and mineralization of osteoblasts by improvising. With enhanced sensitivity it improves the muscle mass which is lean.